Aniston, John Mayor call it quits second time

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"They had some disagreements and decided to not continue to see each other," says one source. "Jen is moving on with her life like she always does. She seems happy." A second source says Mayer broke up with Aniston after she returned from Europe.

In the last few weeks, the actress is spending time with former Friends co-star Courteney Cox Arquette and her yoga instructor-friend Mandy Ingber, while Mayer has been busy getting his new house ready and working in the studio.

However, this is not the first time the 40-year-old Aniston and Mayer aged, 31, have split. In August 2008, they had split for the first time.

The singer at that time held an impromptu press conference outside his gym in New York, explaining to the media, "I ended a relationship to be alone because I don't want to waste somebody's time if something's not right."

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